Peptides

Acetyl Hexapeptide-3 is a cutting-edge anti-aging peptide designed to visibly reduce the appearance of expression lines and wrinkles caused by repeated facial movements. Unlike invasive treatments, this ingredient offers a safe and non-toxic alternative to Botox®, making it highly suitable for cosmetic formulations.

Acetyl  hexapeptide-3  is  a  synthetic  peptide  made  from  a  protein  found  in  Botox.  It’s  primarily  used  in anti-wrinkle and  anti-aging  creams  or  serums. It  works  in  a  similar  fashion  to  Botox;  however,  Acetyl hexapeptide-3 does not need to be injected, which makes it a far more versatile and safer product.

Key Benefits

• Visibly reduces wrinkle depth, number, and area
• Smooths forehead lines, crow’s feet, and other expression-related wrinkles
• Provides a safe, non-invasive alternative to Botox® without irreversible side effects
• Improves skin elasticity and overall appearance

In a 4-week study with volunteers aged 35–55, twice-daily application of Acetyl Hexapeptide-3 significantly reduced wrinkle depth, area, and length as measured by PRIMOS and Cutometer technologies. Results showed visible improvements in both forehead lines and crow’s feet, demonstrating its effectiveness as an anti-aging ingredient.

Acetyl Hexapeptide-8 is a synthetic peptide with neurotransmitter-inhibiting properties which serves an anti-aging purpose in skincare products. Comprising six amino acids linked together, this peptide is recognized for its efficacy in reducing the visibility of wrinkles and fine lines by inhibiting specific muscle movements. It is believed to work similarly to Botox but without the need for injections. Acetyl Hexapeptide enhances the appearance of expression lines, reduces muscle stiffness, and diminishes expression wrinkles. It is believed to interfere with the signals responsible for muscle contractions, leading to a temporary smoothing effect on the skin.

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Acetyl Hexapeptide-8 is a synthetic peptide with neurotransmitter-inhibiting properties which serves an anti-aging purpose in skincare products. Comprising six amino acids linked together, this peptide is recognized for its efficacy in reducing the visibility of wrinkles and fine lines by inhibiting specific muscle movements. It is believed to work similarly to Botox but without the need for injections. Acetyl Hexapeptide enhances the appearance of expression lines, reduces muscle stiffness, and diminishes expression wrinkles. It is believed to interfere with the signals responsible for muscle contractions, leading to a temporary smoothing effect on the skin.

Solution with Acetyl Hexapeptide-8; Glycerin; 112-Hexanediol; Water

Biotinoyl Tripeptide-1 is a cosmetic ingredient which stimulates the metabolism of hair follicle cells specifically targeting hair growth and volume. Through its synergistic combination with biotin, the peptide’s functionality is further enhanced. Biotin is an essential vitamin which plays a crucial role in maintaining the health of hair, improving so its strength and condition. As a result, the hair feels softer and smoother giving it a stronger and healthier appearance.

Copper tripeptide-1 is a small protein composed of the three amino acids glycine, histidine, and lysine combined with the physiologically beneficial mineral copper. Functioning as an anti-aging and as a hair growth stimulating ingredient, increases keratinocyte proliferation and facilitates the synthesis of collagen, a fundamental protein in skin’s structure. This dual action leads to an enhanced skin elasticity and a reduction of wrinkles, fortifying the protection for the skin's barrier function.

Tripeptide-1 Copper is a signal peptide that promotes the degradation of amounts of collagen aggregates outside the scar, the synthesis of normal skin collagen, production of elastin, proteoglycans and glycosaminoglycany, growth rate and migration of different cell types as well as their anti-inflammatory and antioxidation response.

Well-documented skin regeneration activity prompted widespread use of GHK in anti-aging cosmetic products and promotes hair growth.

Dipeptide diaminobutyroyl benzylamide diacetate mimics the effect of waglerin-1, a peptide that is found in the venom of the viper Tropidolaemus Wagleri. Waglerin-1 has been shown to block the nicotinic acetylcholine receptors at the neuromuscular junction, thus inhibiting muscular movement. The function of the Wagerlin-1-mimicking peptide is important for the treatment of lines since facial areas associated with repeated muscle movement are especially susceptible to wrinkle formation.

L-Carnosine, also known simply as Carnosine, is a dipeptide molecule composed of two amino acids: beta-alanine and histidine, naturally present in various tissues of the body. It is an historically known peptide for its powerful different antioxidant properties being the focus of numerous studies. Research indicates that it plays a protective role against glycation, thereby preventing cellular damage and contributing to the improvement of skin texture and appearance reducing roughness and expression lines. As an intriguing and potent ingredient, L-Carnosine holds promise for incorporation into any anti aging product.

L-Glutathione (reduced form) plays an important role in preventing oxidative damage to the skin In addition to its many recognized biological functions, glutathione has also been associated with skin lightening ability. Glutathione utilizes different mechanisms to exert its action as a skin whitening agent at various levels of melanogenesis. Key features of L-Glutathione are smoothing and whitening, lightening dark spots, anti-aging and anti-wrinkles and nourishing the skin.

Myristoyl Pentapeptide-17 is a potent ingredient renowned for its role in promoting eyelash growth. Its mechanism of action involves stimulating the expression of the keratin gene, a pivotal factor in the structural integrity of hair. This stimulation results in the increased proliferation of keratinocytes within the hair bulb, a crucial region for the development and nourishment of hair follicles. Myristoyl Pentapeptide-17 manifests its efficacy by imparting a dual benefit of both thickening and lengthening eyelashes. This transformative action contributes to an overall stronger and more voluminous appearance of the eyelashes, making it a highly sought-after ingredient for inclusion in eyelash serums and other formulations targeted at enhancing lash beauty.

Nonapeptide-1 is a biomimetic peptide which is specifically designed to counter α-MSH. It can prevent the synthesis of melanin,brighten the skin, and reduce the appearance of brown spots.

Palmitoyl hexapeptide-12 offers promising anti-aging benefits for the skin as it has been developed to stimulate elastin synthesis by promoting the stimulation of collagen production. It stimulates collagen and elastin fibroblasts, as well as develops glycosaminoglycans and fibronectin. The intracellular mechanism refers to the way in which it can reduce the production of proinflammatory mediators (IL-1, IL-6, and IL-8) and ultimately slow down the skin matrix’s degradation leading to improved skin aging signals. Consequently, Palmitoyl Hexapeptide-12 is highly valued as a sought-after ingredient in antiaging skincare formulations.

Palmitoyl Tetrapeptide-7 is a short chain of four amino acids: glycine, glutamine, proline, and arginine. This peptide is often used in anti-aging skincare products because it not only stimulates collagen production, but also reduces IL-6 secretion and inflammation calming the skin of external effects such sun exposure and pollution. By promoting collagen production, Palmitoyl Tetrapeptide-7 helps minimize the appearance of fine lines and wrinkles, leading to a smoother and more youthful complexion.

The combination of Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1 help different parts of the skin’s structure to work more effectively, supports the activation of the cutaneous repair process, and in particular at the level of the fragile and UV-damage prone papillary dermis. The solution promotes wrinkle smoothing and improves tone and elasticity.

These two peptides work synergistically to restore and maintain the skin’s youthful appearance by signaling to cells to produce more collagen.

The main active substance is Palmitoyl Tripeptide-1, it is a product obtained by the reaction of palmitic acid with a synthetic tripeptide consisting of the following amino acids: glycine, histidine, lysine.

It acts as a messenger of cutaneous re-structuration and repair, and works synergistically to restore and maintain the skin’s youthful appearance.

Thus, our product Palmitoyl Tripeptide-1 Plus is useful in anti-aging products and wrinkle treatment products such as gels, serums, lotions and creams.

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Palmitoyl Tripeptide-1 Plus composition:

- Palmitoyl Tripeptide-1 (CAS: 147732-56-7)

- Sorbitan Stearate (CAS: 1338-41-6)

- Tribehenin (CAS: 18641-57-1)

- Ethylhexyl Palmitate (CAS 29806-73-3)

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Palmitoyl tripeptide-1 is a peptide that has shown the ability to stimulate collagen synthesis in a human fibroblast culture and prevent its degradation after the exposure to UVA light. It promotes the production of elastin, hyaluronic acid, glycosaminoglycan, and fibronectin with a visible reduction of wrinkles in terms of length, depth, and roughness. Comparable to retinoic acid with regards to its activity, it does not trigger irritation. Collagen and glycosaminoglycan synthesis are stimulated, the epidermis is reinforced, and wrinkles are diminished.

Palmitoyl Tripeptide-5 is a potent anti-aging ingredient that mimics the effects of thrombospondin-1 (TSP-1), an extracellular matrix protein naturally present in the body. TSP-1 is known for enhancing the activity of transforming growth factor beta (TGF), which plays a crucial role in promoting collagen production. The persistent increase in Type I and Type III collagen levels produced by dermal fibroblasts, along with the prevention of collagen degradation, contributes to the peptide's efficacy. By supporting collagen synthesis and inhibiting degradation, Palmitoyl Tripeptide-5 helps reduce the appearance of fine lines and wrinkles, making it a valuable component in skincare formulations designed for rejuvenation and anti-aging benefits.

Transdermal empidermal growth factor (T-EGF) is an eco-friendly and highly efficient cosmetic active. It is the perfect booster ingredient for skin-repairing formulations, whether in a serum or a cream. This naturally occurring protein stimulates fibroblasts to produce collagen and elastin. T-EGF reduces redness in already low dosage (only 0.0002%). Transdermal Epidermal Growth Factor (T-EGF) has proven to be effective in repairing sensitive, dry and damaged skin. It  reduces water loss and helps to hydrate the stratum corneum.

T-EGF is an advanced skincare treatment designed to stimulate cell regeneration and improve skin quality using epidermal growth factors (EGFs). It is intended for cosmetic professionals looking for a cutting-edge anti-aging and skin rejuvenation solution.